JOHANNES ROESSLER & NAOMI EILAN (Eds.)Oxford: Oxford University Press, 2003ISBN 0199245622 (pbk, 415 pages, $39.95)In The Principles of Psychology, William James presents an interesting case of a ‘...

BackgroundGenome-wide association studies (GWAS) provide a powerful means of identifying genetic variants that play a role in common diseases. Such studies present important ethical challenges. An increasing number of GWAS is taking place in lower income countries and there is a pressing need to identify the particular ethical challenges arising in such contexts. In this paper, we draw upon the experiences of the MalariaGEN Consortium to identify specific ethical issues raised by such research in Africa, Asia and Oceania.DiscussionWe explore ethical (...) issues in three key areas: protecting the interests of research participants, regulation of international collaborative genomics research and protecting the interests of scientists in low income countries. With regard to participants, important challenges are raised about community consultation and consent. Genomics research raises ethical and governance issues about sample export and ownership, about the use of archived samples and about the complexity of reviewing such large international projects. In the context of protecting the interests of researchers in low income countries, we discuss aspects of data sharing and capacity building that need to be considered for sustainable and mutually beneficial collaborations.SummaryMany ethical issues are raised when genomics research is conducted on populations that are characterised by lower average income and literacy levels, such as the populations included in MalariaGEN. It is important that such issues are appropriately addressed in such research. Our experience suggests that the ethical issues in genomics research can best be identified, analysed and addressed where ethics is embedded in the design and implementation of such research projects. (shrink)

This open access casebook addresses complex and important ethical challenges arising when health-related research in conducted in the context of epidemics and pandemics. This book provides contextually-rich real-world case studies illustrating research ethics issues encountered by researchers, ethics reviewers and regulators around the globe during the COVID-19 pandemic. The accompanying commentaries outline relevant conceptual approaches and ethical considerations. These promote understanding and reflection on relevant ethical issues, ethical approaches and competing considerations in a manner supporting thoughtful evaluation of their implications (...) for practice. As such the casebook is relevant to academic and professional audiences with an interest in global health, research ethics, and outbreaks and epidemics. (shrink)

Within this paper, we adopt a qualitative process approach to explore how ethical judgments are influenced by spatio-cultural meanings applied to social entrepreneurship in the context of Mozambique. We analyse how such ethical judgments emerged using data gathered over a 4 year period in Maputo. Our findings illustrate three modes used to inform ethical judgments: embracing, rejecting and integrating. These describe how ethical judgments transpire as participants evaluate social entrepreneurship drawing upon related global normative meanings and those embedded within the (...) local context. This analysis offers a critical contribution regarding how ethical judgments regarding social entrepreneurship evolve from negotiation and interaction within a context of multiple spatio-cultural meanings. (shrink)

Stress is increasingly being recognized as one of the main factors that is negatively affecting our health, and therefore there is a need to regulate daily stress and prevent long-term stress. This need seems particularly important for adults with mild intellectual disabilities who have been shown to have more difficulties coping with stress than adults without intellectual disabilities. Hence, the development of music therapy interventions for stress reduction, particularly within populations where needs may be greater, is becoming increasingly important. In (...) order to gain more insight into the practice-based knowledge on how music therapists lower stress levels of their patients with MID during music therapy sessions, we conducted focus group interviews with music therapists working with adults with MID from different countries and clinical institutions in Europe. Results provide an overview of the most-used interventions for stress reduction within and outside of music. Data-analysis resulted in the further specification of therapeutic goals, intervention techniques, the use of musical instruments, and related therapeutic change factors. The main findings indicate that music therapists used little to no receptive interventions for stress reduction, but preferred to use active interventions, which were mainly based on musical improvisation. Results show that three therapy goals for stress relief could be distinguished. The goal of “synchronizing” can be seen as a sub goal because it often precedes working on the other two goals of “tension release” or “direct relaxation,” which can also be seen as two ways of reaching stress reduction in adults with MID through music therapy interventions. Furthermore, the tempo and the dynamics of the music are considered as the most important musical components to reduce stress in adults with MID. Practical implications for stress-reducing music therapy interventions for adults with MID are discussed as well as recommendations for future research. (shrink)

Rural landscapes are facing a loss of biodiversity. To deal with this challenge, landscape governance is seen as an alternative and addition to sectoral policies and a potential way of realizing transformative change for biodiversity. To study transformative change in the Bulb Region, the Netherlands, this study uses a discursive-institutional perspective. A mixed methods approach was used including 50 interviews, participant observation and document analysis. The structuration and institutionalization of three competing landscape discourses were analyzed: a hegemonic discourse rejecting any (...) changes in bulb farming; an emerging discourse aiming to enhance sustainability through innovation; and an unstructured discourse questioning the sustainability of bulb farming. The paper shows that the emerging sustainability discourse strengthens the hegemonic discourse by providing an action repertoire for farmers to deal with changing societal demands, while not questioning the hegemonic view on the landscape. Moreover, an institutionalized landscape discourse can be very stable if discursive (relation between naturalized landscape perspectives, identity and the articulated economic interests) and non-discursive factors (natural-spatial conditions, structure of agricultural sector, embeddedness in international trade) are strongly intertwined, leaving little room for alternative discourses. The sustainability discourse was induced by changes outside the Bulb Region (e.g., legislation), thus raising the question whether landscapes are the appropriate level to expect the initiation of transformative change. For rural transformations to come about, solely relying on policies on the landscape level is not sensible. A mix of policies at both the landscape and higher levels offers more perspective for transformative change. (shrink)

This article examines continuity and change in Star trek’s expression of the American Frontier Myth, moving from an American ideal of imperialist expansion across an unlimited feminized landscape and destruction of Indians and animals in the myth’s early form, to one of benevolent redemption of the Other as misguided or evil alien in the unlimited expanse of outer space in early Star Trek. Analysis of symbol and narrative in Star Trek Voyager show further change, as feminist and environmental ethics are (...) included. Now, movement is toward earth rather than away from it, raced and gendered Others are often internalized rather than projected onto Indians and aliens, and nature is vulnerable and spiritual rather than unlimited and inert. Though women and nature are still linked and idealized as selfless givers, progress is also made as women gain equal rank and air time and men take on some traditionally feminine roles. (shrink)

Background Maternal mental health during the peripartum period is critically important to the wellbeing of mothers and their infants. Numerous studies and clinical trials have focused on various aspects of interventions and treatments for perinatal mental health from the perspective of researchers and medical health professionals. However, less is known about women’s experiences of participating in perinatal mental health research, and the ethical issues that arise. Aim To systematically review the literature on the ethical issues that emerge from pregnant and/or (...) postpartum women’s experiences of taking part in perinatal mental health-related research. Methods Systematic review of nine bibliographic databases, from inception to July 2021. Qualitative, quantitative and mixed method studies were included if they reported on ethical issues experienced by perinatal women. Research ethical issues encompassed any issue relating to women’s experiences of being offered study information, recruitment, consent, retention and respect for autonomy. Titles, abstracts and full text screening, appraisal of the methodological quality of included studies, and data extraction, were conducted independently by two reviewers. Ethical considerations Ethical approval was not required for this systematic review. Findings A total of 9830 unique citations was retrieved. Six studies met the inclusion criteria. Studies were clinically and methodologically heterogenous, and only one was purposively designed to explore women’s experiences. The key finding was the establishment of trust between the researcher and participant in all stages of the research process. Findings are presented according to recruitment and consent processes, participation and retention, and study follow-up and completion. Conclusion The establishment of trust between the researcher and perinatal women leads to a dynamic with research ethical implications relevant to all stages of perinatal mental health-related research. Further research on the research ethical issues experienced by perinatal women is required because of the limited literature. (shrink)

Background: Seeking consent for genetic and genomic research can be challenging, particularly in populations with low literacy levels, and in emergency situations. All of these factors were relevant to the MalariaGEN study of genetic factors influencing immune responses to malaria in northern rural Ghana. This study sought to identify issues arising in practice during the enrolment of paediatric cases with severe malaria and matched healthy controls into the MalariaGEN study. Methods: The study used a rapid assessment incorporating multiple qualitative methods (...) including in depth interviews, focus group discussions and observations of consent processes. Differences between verbal information provided during community engagement processes, and consent processes during the enrolment of cases and controls were identified, as well as the factors influencing the tailoring of such information. Results: MalariaGEN participants and field staff seeking consent were generally satisfied with their understanding of the project and were familiar with aspects of the study relating to malaria. Some genetic aspects of the study were also well understood. Participants and staff seeking consent were less aware of the methodologies employed during genomic research and their implications, such as the breadth of data generated and the potential for future secondary research.Moreover, trust in and previous experience with the Navrongo Health Research Centre which was conducting the research influenced beliefs about the benefits of participating in the MalariaGEN study and subsequent decision-making about research participation. Conclusions: It is important to recognise that some aspects of complex genomic research may be of less interest to and less well understood by research participants and that such gaps in understanding may not be entirely addressed by best practice in the design and conduct of consent processes. In such circumstances consideration needs to be given to additional protections for participants that may need to be implemented in such research, and how best to provide such protections.Capacity building for research ethics committees with limited familiarity with genetic and genomic research, and appropriate engagement with communities to elicit opinions of the ethical issues arising and acceptability of downstream uses of genome wide association data are likely to be important. (shrink)

In the De cognitione angelorum and then in the Ordinatio, Gilles of Rome dedicates long chapters to angelic language. His starting point is a question from Thomas Aquinas about the “secrets of hearts” : they can only be known through corporeal signs, which unwillingly manifest them. Gilles uses Thomas’s postulate that the acts of will are not visible to others, to reject his definition of speaking as a thought voluntarily conveyed to others, and generalizes from his answer: thoughts need to (...) be made manifest through a sign. He develops a theory describing the different types of signs according to their addressees, and analyses them according to several criteria. In particular, from a careful analysis of the signs used by men, Gilles wonders whether the different types of signs used both by men and angels are natural or voluntary, from the point of view of both their composition and their meaning, basing his questioning on the reflections on language and signs in his earlier philosophical commentaries. This insistence on the need for signs will lead Gilles to give different answers to the classic questions about the difference between thought and language, the possibility of addressing a particular angel, and lying. (shrink)

Roger Bacon’s De signis is a major contribution to the history of semantics. However, we know from the author's summary given in the Opus tertium that it has come down to us in an incomplete form. It belongs to the third part of Bacon’s Opus maius, devoted to the “knowledge of languages”. The three sections of the summary in the Opus tertium enable us to understand its organization. The first section presents various arguments in favor of knowledge of languages. The (...) major part of the second section of the summary is related to the “power of words”, which was originally present in the section on mathematics and magic. The third section is not present is the edition of Opus maius III: it was devoted to the study of signs and signification, which corresponds to the De signis, and circulated independently, and to its application to theology, a section that has not been found. Just as the late Compendium studii theologiae, the De signis offers an original treatment of semantic and linguistic questions which are fully embedded in the sophisticated debates that took place in the faculties of arts in Paris and Oxford during the second half of the 13th century. Bacon’s linguistic analysis can be equally relevant for the study of the Bible and theology. (shrink)

Los materiales producidos por entidades ligadas a la salud de las infancias como la OMS, UNICEF o la OPS tienden a enumerar argumentos en contra de las tecnologías, desde los que se desalienta el “uso”, la “exposición” o el “consumo” de pantallas por parte de niñas y niños. Los diseños curriculares para la educación inicial, al contrario, se refieren a las tecnologías como parte de los saberes a enseñar, como oportunidades para la innovación, potenciales recursos para la enseñanza o incluso (...) como rasgos de las llamadas nuevas infancias. En este artículo procuraremos analizar los escenarios de encuentro entre infancias y tecnologías que surgen de ambas fuentes, sobre la hipótesis de que consideran escenarios muy diferentes: no hablan de las mismas tecnologías ni de las mismas infancias. La producción se inscribe en un estudio en curso de la Universidad Pedagógica Nacional, titulado “Infancias, tecnologías digitales y escuela: un análisis desde la educación infantil”. (shrink)

The massive increase of data generated by heterogeneous sources requires the development of computer tools enabling their semantic interoperability. Applied ontologies aim at fulfilling such needs. We will show in this article the central role that philosophical ontology can play for applied ontology, with a focus on biomedical ontologies; and reciprocally, how applied ontology can enlighten some classical issues in philosophical ontology, by considering the following question: Is disease a natural kind?

La nature catégorielle de la « voix », substance, quantité ou qualité, fait débat chez les grammairiens et logiciens du début du xii e siècle. Les discussions grammaticales se lisent dans les commentaires sur Priscien, aux chapitres initiaux du De uoce et du De littera, dont on édite ici plusieurs témoins majeurs, trois versions des Glosulae super Priscianum et les Notae Dunelmenses qui en dérivent, témoins anonymes où se lit l’influence de Guillaume de Champeaux. Les arguments tirés de ces textes (...) sont repris dans les commentaires sur les Catégories, faisant apparaître les enjeux physique, logique, ontologique et sémantique des débats sur la voix. (shrink)

L'enseignement universitaire du XIIIe siecle se fonde sur le commentaire et la dispute. La Sophistria de Robertus Anglicus (1260-70), dont est proposee ici l'edition critique accompagnee d'une etude historique et doctrinale detaillee, est un temoin exceptionnel de cette pratique de l'enseignement des arts par mode de sophisme, surtout developpe pour la logique et la grammaire. Il s'agit d'une collection d'une trentaine de sophismes, organisee de facon systematique, et preservee dans huit manuscrits. On y voit ainsi, en partant du sophisme, enonce (...) problematique, le maitre avancer des arguments, avec ou contre ses bacheliers, a propos de toutes les difficultes qu'il contient, les arguments et solutions fournissant au bout du compte un expose general de la syntaxe latine. La Sophistria s'insere dans une tradition de la grammaire speculative, qui, contrairement aux grands traites posterieurs sur les Modes de signifier, met l'accent sur la semanticite plus que sur la grammaticalite: un enonce incorrect peut etre admis si l'on comprend la raison (ratio) qui rend compte de sa deviation. Cette approche, comme l'application tres caracteristique de la Physique d'Aristote a la grammaire, permet de rapprocher la Sophistria de l'enseignement parisien des maitres anglais de la generation precedente, Robert Kilwardby et Roger Bacon, l'appartenance au milieu parisien se confirmant par sa proximite avec le Tractatus de Gosvin de Marbais. (shrink)

Evoquees par Augustin, les Categories d'Aristote, accompagnees de l'introduction de Porphyre, sont traduites et commentees par Boece. Deja exposee dans le monde arabo-musulman, cette oeuvre devait faire l'objet de nombreux commentaires dans le monde latin, sans interruption, du temps d'Abelard jusqu'a la fin du Moyen Age. De l'etude du langage a la theorie de l'etre, ouvrant sur la philosophie naturelle et la theologie, les interrogations que suscitent les Categories sont multiformes. Elles concernent le statut des categories, leur nombre, les differents (...) types de predication, ou la nature particuliere de certaines categories comme la relation ou la quantite. Le premier chapitre du traite, avec sa distinction entre equivoques, univoques et paronymes, suscite des reflexions sur les variations semantiques, les transferts de sens, et donne en meme temps naissance a la theorie de l'analogie de l'etant, aux implications metaphysiques et theologiques majeures. Les vingt deux essais de ce receuil explorent, a travers l'etude d'auteurs connus ou moins connus, les multiples facettes de cette riche tradition medievale de commentaires sur les Categories d'Aristote. (shrink)

A compelling look at the problem of evil in modern thought, from the Inquisition to global terrorism Evil threatens human reason, for it challenges our hope that the world makes sense. For eighteenth-century Europeans, the Lisbon earthquake was manifest evil. Today we view evil as a matter of human cruelty, and Auschwitz as its extreme incarnation. Examining our understanding of evil from the Inquisition to contemporary terrorism, Susan Neiman explores who we have become in the three centuries that separate (...) us from the early Enlightenment. In the process, she rewrites the history of modern thought and points philosophy back to the questions that originally animated it. Whether expressed in theological or secular terms, evil poses a problem about the world's intelligibility. It confronts philosophy with fundamental questions: Can there be meaning in a world where innocents suffer? Can belief in divine power or human progress survive a cataloging of evil? Is evil profound or banal? Neiman argues that these questions impelled modern philosophy. Traditional philosophers from Leibniz to Hegel sought to defend the Creator of a world containing evil. Inevitably, their efforts—combined with those of more literary figures like Pope, Voltaire, and the Marquis de Sade—eroded belief in God's benevolence, power, and relevance, until Nietzsche claimed He had been murdered. They also yielded the distinction between natural and moral evil that we now take for granted. Neiman turns to consider philosophy's response to the Holocaust as a final moral evil, concluding that two basic stances run through modern thought. One, from Rousseau to Arendt, insists that morality demands we make evil intelligible. The other, from Voltaire to Adorno, insists that morality demands that we don't. Beautifully written and thoroughly engaging, this book tells the history of modern philosophy as an attempt to come to terms with evil. It reintroduces philosophy to anyone interested in questions of life and death, good and evil, suffering and sense. Featuring a substantial new afterword by Neiman that raises provocative questions about Hannah Arendt's take on Adolf Eichmann and the rationale behind the Hiroshima bombing, this Princeton Classics edition introduces a new generation of readers to this eloquent and thought-provoking meditation on good and evil, life and death, and suffering and sense. (shrink)

In the De cognitione angelorum and then in the Ordinatio, Gilles of Rome dedicates long chapters to angelic language. His starting point is a question from Thomas Aquinas about the “secrets of hearts” : they can only be known through corporeal signs, which unwillingly manifest them. Gilles uses Thomas’s postulate that the acts of will are not visible to others, to reject his definition of speaking as a thought voluntarily conveyed to others, and generalizes from his answer: thoughts need to (...) be made manifest through a sign. He develops a theory describing the different types of signs according to their addressees, and analyses them according to several criteria. In particular, from a careful analysis of the signs used by men, Gilles wonders whether the different types of signs used both by men and angels are natural or voluntary, from the point of view of both their composition and their meaning, basing his questioning on the reflections on language and signs in his earlier philosophical commentaries. This insistence on the need for signs will lead Gilles to give different answers to the classic questions about the difference between thought and language, the possibility of addressing a particular angel, and lying. (shrink)

Quelle place est faite au droit des hommes dans une société chrétienne? On étudiera d'abord l'entrée du droit dans l'exégèse, avec Hugues de Saint-Cher, puis le cas, privilégié, du serment et du mensonge, ici analysé dans l'oeuvre de Pierre de Jean Olivi (ca 1280). On verra émerger les notions d'engagement et d'obligation - envers le prochain et envers Dieu. L'obligation est réalisée par la prononciation de paroles, qui prime sur tout autre circonstance de l'acte. Elle repose sur la reconnaissance d'une (...) norme qui renvoie non seulement à des propositions exprimées, mais aussi à des implicites tacitement admis dans une communauté. (shrink)

Le langage, la signification, la référence ont fait l’objet d’une grande attention au Moyen Âge, de la part des spécialistes des arts du langage. Pourtant, ils n’ont quasiment pas lu Augustin. Les théologiens, par contre, ont tiré grand profit des analyses augustiniennes. Henri de Gand a lu le De dialectica, en articulant autour de ce petit traité les autres textes d’Augustin portant sur le langage et les signes, afin d’élaborer une théorie du « langage vocal », préliminaire à toute réflexion (...) sur les noms divins, l’ineffabilité, l’analogie ou la propriété des noms. Ces textes forment également le socle des analyses élaborées par les théologiens sur le « parler des anges ». Par ailleurs, les chapitres sur les signes sacramentels doivent à la pensée augustinienne une analyse du signe, tirée du De doctrina christiana. Les théologiens insistent sur le caractère doublement relationnel du signe : signe de quelque chose, signe pour quelqu’un. Le caractère intentionnel de la prononciation de la formule du baptême ou du mariage est traité à partir des opuscules consacrés au mensonge ( De mendacio, Contra mendacium ). L’analyse de la causalité sacramentelle, et particulièrement celle de la causalité conventionnelle fondée sur le pacte, se construit sur la notion augustinienne de consensus, repensée dans le cadre d’une réflexion sur les signes magiques par Guillaume d’Auvergne, mais également sur la théorie de la relation telle qu’elle est élaborée dans le De Trinitate. Roger Bacon, qui fut maître ès arts avant de devenir franciscain, saura lire ces analyses des théologiens, et, en articulant les sources augustiniennes avec les sources logico-grammaticales utilisées par les Artistae, produire une théorie générale des signes. (shrink)

Les discussions sur la nature catégorielle de la « voix » se développent en parallèle, au début du xii e siècle, dans les commentaires sur les Catégories et dans les commentaires sur les Institutiones de Priscien (les Glosulae super Priscianum ). Elles ont des enjeux multiples, touchant à la nature de la substance et de la qualité, de la perception, de l’individualité et de l’indivisibilité, de la nature des corps, et sont liées à la question des universaux. En prenant en (...) série les arguments développés dans ces témoins anonymes, on peut reconstruire le développement des discussions et les différentes positions, en particulier celles de Guillaume de Champeaux et d’Abélard. (shrink)

Les milliers de milliards de dollars injectés pour renflouer les institutions financières pèseront sur les économies intérieures pour les années à venir. Mais les interventions massives des États ont-elles signé la fin du modèle néolibéral ? Au plan idéologique, les créations de richesse mirifiques de la haute finance ont été son principal instrument de légitimation. On a senti, et pas seulement à gauche, que le paradigme néolibéral ne sortirait pas indemne de la crise, qui pouvait même porter un coup fatal (...) à l’hégémonie américaine. L’humiliation des géants de Wall Street semblait indiquer que le monde se trouvait au seuil d’une nouvelle ère. Entre-temps, le système financier a été stabilisé sans qu’aucun de ses problèmes de fond n’ait été résolu. Malgré le déferlement d’analyses consacrées à la crise, sa portée historique reste obscure. À quoi la crise de septembre 2008 a-t-elle mis fin ? À quoi n’a-t-elle pas mis fin ? (shrink)

La méthode adoptée dans le Vocabulaire européen des philosophies peut-elle être taxée de « relativiste » comme l’écrit Carlo Ginzburg, et plus précisément de mener au « relativisme sceptique »? L’on vise ici à répondre par la négative en montrant les proximités entre la démarche du VEP et certains travaux de l’auteur lui-même. Si le VEP n’est pas un dictionnaire d’« ethnophilologie », et se centre sur les traductions du vocabulaire philosophique, les enjeux politiques sont essentiels. Il s’agit, en prenant (...) de la distance par rapport à sa propre langue, de construire des comparables, en étant aussi bien contre l’universalisme abstrait que contre le culturalisme relativiste qui conduit à l’incommensurabilité. (shrink)

La méthode adoptée dans le Vocabulaire européen des philosophies peut-elle être taxée de « relativiste » comme l’écrit Carlo Ginzburg, et plus précisément de mener au « relativisme sceptique »? L’on vise ici à répondre par la négative en montrant les proximités entre la démarche du VEP et certains travaux de l’auteur lui-même. Si le VEP n’est pas un dictionnaire d’« ethnophilologie », et se centre sur les traductions du vocabulaire philosophique, les enjeux politiques sont essentiels. Il s’agit, en prenant (...) de la distance par rapport à sa propre langue, de construire des comparables, en étant aussi bien contre l’universalisme abstrait que contre le culturalisme relativiste qui conduit à l’incommensurabilité. (shrink)

La distinction de droit pénal entre la conduitemalum in seetmalum prohibitumest vieille de cinq siècles dans les juridictions de common law, et pourtant son sens autant que son utilité continuent d’être débattus. Je me joins à la mêlée, en faisant valoir que les conditions ne peuvent pas être interprétées littéralement, mais que il existe un moyen d’établir la distinction qui est à la fois plausible et utile. Une conduitemala in seest un comportement quidoitêtre interdit dans toute société politique juste, alors (...) que la conduitemala prohibita peutêtre criminalisée, mais nedoitpas absolument l’être. Je sollicite dans mon explication des concepts de la théorie du contrat social. (shrink)